Antimicrobial agent-2

Modify Date: 2024-01-03 11:09:55

Antimicrobial agent-2 Structure
Antimicrobial agent-2 structure
Common Name Antimicrobial agent-2
CAS Number 2412592-33-5 Molecular Weight 330.36
Density N/A Boiling Point N/A
Molecular Formula C16H14N2O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antimicrobial agent-2


Antimicrobial agent-2 (compound V-a) is a broad-spectrum antimicrobial agent, possessing inhibitory activity against various Gram-positive and -negative bacteria. Antimicrobial agent-2 has excellent inhibitory effect on Methicillin-resistant Staphylococcus aureus (MRSA) with a MIC of 1 μg/mL. Antimicrobial agent-2 can effectively damage the membrane and lead to the leakage of protein, also can induce the generation of ROS. Antimicrobial agent-2 exhibits low toxicity, no obvious resistance and good bioavailability[1].

 Names

Name Antimicrobial agent-2

 Antimicrobial agent-2 Biological Activity

Description Antimicrobial agent-2 (compound V-a) is a broad-spectrum antimicrobial agent, possessing inhibitory activity against various Gram-positive and -negative bacteria. Antimicrobial agent-2 has excellent inhibitory effect on Methicillin-resistant Staphylococcus aureus (MRSA) with a MIC of 1 μg/mL. Antimicrobial agent-2 can effectively damage the membrane and lead to the leakage of protein, also can induce the generation of ROS. Antimicrobial agent-2 exhibits low toxicity, no obvious resistance and good bioavailability[1].
Related Catalog
Target

MIC: 1 μg/mL (MRSA), 2 μg/mL (Enterococcus faecalis)[1]

References

[1]. Yang XC, et al. Coumarin thiazoles as unique structural skeleton of potential antimicrobial agents. Bioorg Chem. 2022;124:105855.

 Chemical & Physical Properties

Molecular Formula C16H14N2O4S
Molecular Weight 330.36