2412592-33-5

2412592-33-5 structure
2412592-33-5 structure
  • Name: Antimicrobial agent-2
  • Chemical Name: Antimicrobial agent-2
  • CAS Number: 2412592-33-5
  • Molecular Formula: C16H14N2O4S
  • Molecular Weight: 330.36
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK ROS
  • Create Date: 2022-07-01 17:12:21
  • Modify Date: 2024-01-03 11:09:55
  • Antimicrobial agent-2 (compound V-a) is a broad-spectrum antimicrobial agent, possessing inhibitory activity against various Gram-positive and -negative bacteria. Antimicrobial agent-2 has excellent inhibitory effect on Methicillin-resistant Staphylococcus aureus (MRSA) with a MIC of 1 μg/mL. Antimicrobial agent-2 can effectively damage the membrane and lead to the leakage of protein, also can induce the generation of ROS. Antimicrobial agent-2 exhibits low toxicity, no obvious resistance and good bioavailability[1].

Name Antimicrobial agent-2
Description Antimicrobial agent-2 (compound V-a) is a broad-spectrum antimicrobial agent, possessing inhibitory activity against various Gram-positive and -negative bacteria. Antimicrobial agent-2 has excellent inhibitory effect on Methicillin-resistant Staphylococcus aureus (MRSA) with a MIC of 1 μg/mL. Antimicrobial agent-2 can effectively damage the membrane and lead to the leakage of protein, also can induce the generation of ROS. Antimicrobial agent-2 exhibits low toxicity, no obvious resistance and good bioavailability[1].
Related Catalog
Target

MIC: 1 μg/mL (MRSA), 2 μg/mL (Enterococcus faecalis)[1]

References

[1]. Yang XC, et al. Coumarin thiazoles as unique structural skeleton of potential antimicrobial agents. Bioorg Chem. 2022;124:105855.

Molecular Formula C16H14N2O4S
Molecular Weight 330.36