Anti-NASH agent 1
Modify Date: 2025-11-25 09:53:18
Anti-NASH agent 1 structure
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Common Name | Anti-NASH agent 1 | ||
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| CAS Number | 2409685-41-0 | Molecular Weight | 423.54 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H33NO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Anti-NASH agent 1Anti-NASH agent 1 (compound 3d)，a derivative of Elafibranor (HY-16737)，is a potent agonist of PPAR-α/δ，targeting to nonalcoholic steatohepatitis (NASH). Anti-NASH agent 1 (3-10 mg/kg; 4 weeks) improves hyperlipidemia，liver fat degeneration and liver inflammation in Methionine-choline deficiency (MCD) induced NASH mice model. Anti-NASH agent 1 shows low liver toxicity and potent liver protection effect[1]. |
| Name | Anti-NASH agent 1 |
|---|
| Description | Anti-NASH agent 1 (compound 3d)，a derivative of Elafibranor (HY-16737)，is a potent agonist of PPAR-α/δ，targeting to nonalcoholic steatohepatitis (NASH). Anti-NASH agent 1 (3-10 mg/kg; 4 weeks) improves hyperlipidemia，liver fat degeneration and liver inflammation in Methionine-choline deficiency (MCD) induced NASH mice model. Anti-NASH agent 1 shows low liver toxicity and potent liver protection effect[1]. |
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| Related Catalog | |
| Target |
PPAR-α/δ[1] |
| References |
| Molecular Formula | C26H33NO4 |
|---|---|
| Molecular Weight | 423.54 |
| InChIKey | JMNQFYWMYKSSSA-NTEUORMPSA-N |
| SMILES | CNc1ccc(C(=O)C=Cc2cc(C)c(OC(C)(C)C(=O)OC(C)(C)C)c(C)c2)cc1 |