Anti-NASH agent 1
Names
[ CAS No. ]:
2409685-41-0
[ Name ]:
Anti-NASH agent 1
Biological Activity
[Description]:
Anti-NASH agent 1 (compound 3d),a derivative of Elafibranor (HY-16737),is a potent agonist of PPAR-α/δ,targeting to nonalcoholic steatohepatitis (NASH). Anti-NASH agent 1 (3-10 mg/kg; 4 weeks) improves hyperlipidemia,liver fat degeneration and liver inflammation in Methionine-choline deficiency (MCD) induced NASH mice model. Anti-NASH agent 1 shows low liver toxicity and potent liver protection effect[1].
[Related Catalog]:
[Target]
PPAR-α/δ[1]
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C26H33NO4
[ Molecular Weight ]:
423.54