P-gp inhibitor 2

Modify Date: 2025-08-24 13:45:34

P-gp inhibitor 2 Structure
P-gp inhibitor 2 structure
Common Name P-gp inhibitor 2
CAS Number 2408406-89-1 Molecular Weight 498.53
Density N/A Boiling Point N/A
Molecular Formula C29H26N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of P-gp inhibitor 2


P-gp inhibitor 2 is a potent P-gp inhibitor. P-gp inhibitor 2 shows reverse Doxorubicin resistance (IC50=0.22 µM) in P-gp overexpressing human colorectal carcinoma cells (SW600 Ad300)[1].

 Names

Name P-gp inhibitor 2

 P-gp inhibitor 2 Biological Activity

Description P-gp inhibitor 2 is a potent P-gp inhibitor. P-gp inhibitor 2 shows reverse Doxorubicin resistance (IC50=0.22 µM) in P-gp overexpressing human colorectal carcinoma cells (SW600 Ad300)[1].
Related Catalog
In Vitro P-gp inhibitor 2 (compound 2) exhibits no cytotoxicity (IC50>30 µM) toward human carcinoma (SW600) cells[1].
References

[1]. Dewa AA, et al. Neochrysosporazines: Precursor-Directed Biosynthesis Defines a Marine-Derived Fungal Natural Product P-Glycoprotein Inhibitory Pharmacophore. J Med Chem. 2022, 65(3):2610-2622.

 Chemical & Physical Properties

Molecular Formula C29H26N2O6
Molecular Weight 498.53
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