GAK inhibitor 2

Modify Date: 2025-08-27 03:04:42

GAK inhibitor 2 Structure
GAK inhibitor 2 structure
Common Name GAK inhibitor 2
CAS Number 2396706-31-1 Molecular Weight 385.48
Density N/A Boiling Point N/A
Molecular Formula C20H23N3O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GAK inhibitor 2


GAK inhibitor 2 (Compound 14g) is a potent cyclin G-associated kinase (GAK) inhibitor with an IC50 of 0.024 μM. GAK inhibitor 2 shows antiviral activity with an EC50 of 1.049 μM against dengue virus (DENV)[1].

 Names

Name GAK inhibitor 2

 GAK inhibitor 2 Biological Activity

Description GAK inhibitor 2 (Compound 14g) is a potent cyclin G-associated kinase (GAK) inhibitor with an IC50 of 0.024 μM. GAK inhibitor 2 shows antiviral activity with an EC50 of 1.049 μM against dengue virus (DENV)[1].
Related Catalog
Target

IC50: 0.024 μM (GAK)[1]

References

[1]. Martinez-Gualda B, et al. Structure-activity relationship study of the pyridine moiety of isothiazolo[4,3-b]pyridines as antiviral agents targeting cyclin G-associated kinase. Bioorg Med Chem. 2020 Jan 1;28(1):115188.

 Chemical & Physical Properties

Molecular Formula C20H23N3O3S
Molecular Weight 385.48
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