3alpha,21-dihydroxy-5alpha-pregnane-11,20-dione 21-acetate
Modify Date: 2024-01-09 21:28:48
3alpha,21-dihydroxy-5alpha-pregnane-11,20-dione 21-acetate structure
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Common Name | 3alpha,21-dihydroxy-5alpha-pregnane-11,20-dione 21-acetate | ||
|---|---|---|---|---|
| CAS Number | 23930-37-2 | Molecular Weight | 390.51300 | |
| Density | 1.164g/cm3 | Boiling Point | 523.6ºC at 760mmHg | |
| Molecular Formula | C23H34O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 175.1ºC | |
Use of 3alpha,21-dihydroxy-5alpha-pregnane-11,20-dione 21-acetateAlphadolone acetate (Alfadolone acetate) is a steroid anaesthetic, with antinociception[1]. |
| Name | (3α,5α)-3-Hydroxy-11,20-dioxopregnan-21-yl acetate |
|---|---|
| Synonym | More Synonyms |
| Description | Alphadolone acetate (Alfadolone acetate) is a steroid anaesthetic, with antinociception[1]. |
|---|---|
| Related Catalog | |
| In Vivo | Alphadolone acetate (anaesthetized with a 3:1 mixture of Alphaxalone and Alphadolone acetate; i.m.) blocks the oestrogen-stimulated luteinizing hormone (LH) surge and impairs pulsatile secretion in female rats, when combined with alphaxalonet[2]. Alphadolone acetate (14 mL/kg; i.p.; single dosage) decreases serum concentrations of LH in castrated rats[3]. Animal Model: Inbred Wistar-derived colony female rats (intramuscularly injected with 20 µg/100g oestradiol benzoate)[2] Dosage: Anaesthetized with a 3 :1 mixture of Alphaxalone and Alphadolone acetate Administration: i.m. Result: Blocked the oestrogen-stimulated LH surge and impairs pulsatile secretion. Animal Model: Male Sprague-Dawley rats (orchidectomized; aged 90-120 days and weighing 300-350 g)[3] Dosage: 14 mL/kg Administration: i.p.; single dosage Result: Decreased serum concentrations of LH. |
| Density | 1.164g/cm3 |
|---|---|
| Boiling Point | 523.6ºC at 760mmHg |
| Molecular Formula | C23H34O5 |
| Molecular Weight | 390.51300 |
| Flash Point | 175.1ºC |
| Exact Mass | 390.24100 |
| PSA | 80.67000 |
| LogP | 3.31740 |
| Vapour Pressure | 3.75E-13mmHg at 25°C |
| Index of Refraction | 1.53 |
| 2-phenoxyethyl 4-(2,3-dimethoxyphenyl)-7-(4-methoxyphenyl)-2-methyl-5-oxo-1,4,6,7,8-pentahydroquinoline-3-carboxylate |
| 2-phenoxyethyl 4-(2,3-dimethoxyphenyl)-7-(4-methoxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate |
| endo-Bicyclo<3.3.1>nonan-3-ol |
| exo-Bicyclo<3.3.1>nonanol-3 |
| exo-Bicyclo<3.3.1>nonan-3-ol |