Cavrotolimod

Modify Date: 2024-04-06 20:46:20

Cavrotolimod structure	Common Name	Cavrotolimod
	CAS Number	2378664-12-9	Molecular Weight	9142.88
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀₀H₄₂₃N₇₁O₁₆₁P₂₆S₂₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cavrotolimod

Cavrotolimod is an immunostimulatory spherical nucleic acid (SNA) modified with type B CpG oligonucleotides designed to agonize TLR9 and elicit immune responses useful in oncology applications.

Name	Cavrotolimod

Description	Cavrotolimod is an immunostimulatory spherical nucleic acid (SNA) modified with type B CpG oligonucleotides designed to agonize TLR9 and elicit immune responses useful in oncology applications.
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Others
References	[1]. Daniel WL, Lorch U, Mix S, Bexon AS. A first-in-human phase 1 study of cavrotolimod, a TLR9 agonist spherical nucleic acid, in healthy participants: Evidence of immune activation. Front Immunol. 2022;13:1073777. [2]. Rubatto M, Sciamarrelli N, Borriello S, et al. Classic and new strategies for the treatment of advanced melanoma and non-melanoma skin cancer. Front Med (Lausanne). 2023;9:959289.

Description

Cavrotolimod is an immunostimulatory spherical nucleic acid (SNA) modified with type B CpG oligonucleotides designed to agonize TLR9 and elicit immune responses useful in oncology applications.

Related Catalog

Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR)

Research Areas >> Others

References

[1]. Daniel WL, Lorch U, Mix S, Bexon AS. A first-in-human phase 1 study of cavrotolimod, a TLR9 agonist spherical nucleic acid, in healthy participants: Evidence of immune activation. Front Immunol. 2022;13:1073777.

[2]. Rubatto M, Sciamarrelli N, Borriello S, et al. Classic and new strategies for the treatment of advanced melanoma and non-melanoma skin cancer. Front Med (Lausanne). 2023;9:959289.

Molecular Formula	C₃₀₀H₄₂₃N₇₁O₁₆₁P₂₆S₂₃
Molecular Weight	9142.88

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Cavrotolimod

Use of Cavrotolimod

Names

Cavrotolimod Biological Activity

Chemical & Physical Properties