Cavrotolimod

Names

[ Name ]:
Cavrotolimod

Biological Activity

[Description]:

Cavrotolimod is an immunostimulatory spherical nucleic acid (SNA) modified with type B CpG oligonucleotides designed to agonize TLR9 and elicit immune responses useful in oncology applications.

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR)

Research Areas >> Others

[References]

[1]. Daniel WL, Lorch U, Mix S, Bexon AS. A first-in-human phase 1 study of cavrotolimod, a TLR9 agonist spherical nucleic acid, in healthy participants: Evidence of immune activation. Front Immunol. 2022;13:1073777.

[2]. Rubatto M, Sciamarrelli N, Borriello S, et al. Classic and new strategies for the treatment of advanced melanoma and non-melanoma skin cancer. Front Med (Lausanne). 2023;9:959289.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₀₀H₄₂₃N₇₁O₁₆₁P₂₆S₂₃

[ Molecular Weight ]:
9142.88

Related Compounds

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