2378664-12-9

2378664-12-9 structure

Name: Cavrotolimod
Chemical Name: Cavrotolimod
CAS Number: 2378664-12-9
Molecular Formula: C₃₀₀H₄₂₃N₇₁O₁₆₁P₂₆S₂₃
Molecular Weight: 9142.88
Catalog: Signaling Pathways Immunology/Inflammation Toll-like Receptor (TLR)
Create Date: 2023-06-19 20:14:47
Modify Date: 2025-11-27 18:41:31
Cavrotolimod is an immunostimulatory spherical nucleic acid (SNA) modified with type B CpG oligonucleotides designed to agonize TLR9 and elicit immune responses useful in oncology applications.

Name	Cavrotolimod

Description	Cavrotolimod is an immunostimulatory spherical nucleic acid (SNA) modified with type B CpG oligonucleotides designed to agonize TLR9 and elicit immune responses useful in oncology applications.
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Others
References	[1]. Daniel WL, Lorch U, Mix S, Bexon AS. A first-in-human phase 1 study of cavrotolimod, a TLR9 agonist spherical nucleic acid, in healthy participants: Evidence of immune activation. Front Immunol. 2022;13:1073777. [2]. Rubatto M, Sciamarrelli N, Borriello S, et al. Classic and new strategies for the treatment of advanced melanoma and non-melanoma skin cancer. Front Med (Lausanne). 2023;9:959289.

Molecular Formula	C₃₀₀H₄₂₃N₇₁O₁₆₁P₂₆S₂₃
Molecular Weight	9142.88