(S,R,S)-AHPC-Me-C10-NH2

Modify Date: 2025-08-27 09:12:41

(S,R,S)-AHPC-Me-C10-NH2 Structure
(S,R,S)-AHPC-Me-C10-NH2 structure
Common Name (S,R,S)-AHPC-Me-C10-NH2
CAS Number 2376139-52-3 Molecular Weight 627.88
Density N/A Boiling Point N/A
Molecular Formula C34H53N5O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S,R,S)-AHPC-Me-C10-NH2


(S,R,S)-AHPC-Me-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C10-NH2 can be used in PROTAC MS432 (HY-130602)[1].

 Names

Name (S,R,S)-AHPC-Me-C10-NH2

 (S,R,S)-AHPC-Me-C10-NH2 Biological Activity

Description (S,R,S)-AHPC-Me-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C10-NH2 can be used in PROTAC MS432 (HY-130602)[1].
Related Catalog
Target

VHL

In Vitro MS432 is a first-in-class and highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2[1].
References

[1]. Wei J, et al. Discovery of a First-in-Class Mitogen-Activated Protein Kinase Kinase 1/2 Degrader. J Med Chem. 2019 Dec 12;62(23):10897-10911.

 Chemical & Physical Properties

Molecular Formula C34H53N5O4S
Molecular Weight 627.88
InChIKey AJVUUWWUFQQMNH-GOGGMHKJSA-N
SMILES Cc1ncsc1-c1ccc(C(C)NC(=O)C2CC(O)CN2C(=O)C(NC(=O)CCCCCCCCCCN)C(C)(C)C)cc1

 Safety Information

Hazard Codes Xi
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