2376139-52-3

2376139-52-3 structure

Name: (S,R,S)-AHPC-Me-C10-NH2
Chemical Name: (S,R,S)-AHPC-Me-C10-NH2
CAS Number: 2376139-52-3
Molecular Formula: C₃₄H₅₃N₅O₄S
Molecular Weight: 627.88
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2020-04-11 19:46:58
Modify Date: 2025-08-27 09:12:41
(S,R,S)-AHPC-Me-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C10-NH2 can be used in PROTAC MS432 (HY-130602)[1].

Name	(S,R,S)-AHPC-Me-C10-NH2

Description	(S,R,S)-AHPC-Me-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C10-NH2 can be used in PROTAC MS432 (HY-130602)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	VHL
In Vitro	MS432 is a first-in-class and highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2[1].
References	[1]. Wei J, et al. Discovery of a First-in-Class Mitogen-Activated Protein Kinase Kinase 1/2 Degrader. J Med Chem. 2019 Dec 12;62(23):10897-10911.

Molecular Formula	C₃₄H₅₃N₅O₄S
Molecular Weight	627.88

Hazard Codes	Xi