Kallikrein 5-IN-2

Modify Date: 2025-09-11 11:06:16

Kallikrein 5-IN-2 structure	Common Name	Kallikrein 5-IN-2
	CAS Number	2361160-57-6	Molecular Weight	398.46
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₂N₆O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Kallikrein 5-IN-2

Kallikrein 5-IN-2 (compound 21) is a selective Kallikrein KLK5 inhibitor (pIC50=7.1). KLK5 inhibition may normalise epidermal shedding and reduce the associated inflammation and itching[1].

Name	Kallikrein 5-IN-2

Description	Kallikrein 5-IN-2 (compound 21) is a selective Kallikrein KLK5 inhibitor (pIC50=7.1). KLK5 inhibition may normalise epidermal shedding and reduce the associated inflammation and itching[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	Kallikrein 5[1]
References	[1]. Walker AL, et al. Structure guided drug design to develop kallikrein 5 inhibitors to treat Netherton syndrome. Bioorg Med Chem Lett. 2019 Jun 15;29(12):1454-1458.

Molecular Formula	C₂₃H₂₂N₆O
Molecular Weight	398.46

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