2361160-57-6

2361160-57-6 structure

2361160-57-6 structure

Name: Kallikrein 5-IN-2
Chemical Name: Kallikrein 5-IN-2
CAS Number: 2361160-57-6
Molecular Formula: C₂₃H₂₂N₆O
Molecular Weight: 398.46
Catalog: Research Areas Others
Create Date: 2023-05-19 08:03:08
Modify Date: 2024-01-23 09:08:11
Kallikrein 5-IN-2 (compound 21) is a selective Kallikrein KLK5 inhibitor (pIC50=7.1). KLK5 inhibition may normalise epidermal shedding and reduce the associated inflammation and itching[1].

Name	Kallikrein 5-IN-2

Description	Kallikrein 5-IN-2 (compound 21) is a selective Kallikrein KLK5 inhibitor (pIC50=7.1). KLK5 inhibition may normalise epidermal shedding and reduce the associated inflammation and itching[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	Kallikrein 5[1]
References	[1]. Walker AL, et al. Structure guided drug design to develop kallikrein 5 inhibitors to treat Netherton syndrome. Bioorg Med Chem Lett. 2019 Jun 15;29(12):1454-1458.

Molecular Formula	C₂₃H₂₂N₆O
Molecular Weight	398.46