JMS-17-2 hydrochloride
Modify Date: 2024-01-09 15:01:28
JMS-17-2 hydrochloride structure
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Common Name | JMS-17-2 hydrochloride | ||
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| CAS Number | 2341841-07-2 | Molecular Weight | 456.41 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H27Cl2N3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of JMS-17-2 hydrochlorideJMS-17-2 hydrochloride is a potent and selective CX3CR1 antagonist with an IC50 of 0.32 nM. JMS-17-2 hydrochloride impairs metastatic seeding and colonization of breast cancer cells[1]. |
| Name | JMS-17-2 hydrochloride |
|---|
| Description | JMS-17-2 hydrochloride is a potent and selective CX3CR1 antagonist with an IC50 of 0.32 nM. JMS-17-2 hydrochloride impairs metastatic seeding and colonization of breast cancer cells[1]. |
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| Related Catalog | |
| Target |
IC50: 0.32 nM (CX3CR1)[1] |
| In Vivo | JMS-17-2 (10 mg/kg; aministered i.p.; twice a day for three weeks) causes a dramatic reduction of tumors in both skeleton and visceral organs in SCID mice[1]. Animal Model: SCID mice (~25g) with MDA-231 xenograft[1] Dosage: 10 mg/kg Administration: Aministered i.p.; twice a day for three weeks Result: Caused a dramatic reduction of tumors in both skeleton and visceral organs. |
| References |
| Molecular Formula | C25H27Cl2N3O |
|---|---|
| Molecular Weight | 456.41 |