1380392-05-1
1380392-05-1 structure
- Name: JMS-17-2
- Chemical Name: 5-{3-[4-(4-Chlorophenyl)-1-piperidinyl]propyl}pyrrolo[1,2-a]quinoxalin-4(5H)-one
- CAS Number: 1380392-05-1
- Molecular Formula: C25H26ClN3O
- Molecular Weight: 419.95
- Catalog: Signaling Pathways GPCR/G Protein CXCR
- Create Date: 2018-06-11 11:24:22
- Modify Date: 2025-08-25 18:50:30
-
JMS-17-2 is a potent and selective CX3CR1 antagonist with an IC50 of 0.32 nM[1].
| Name | 5-{3-[4-(4-Chlorophenyl)-1-piperidinyl]propyl}pyrrolo[1,2-a]quinoxalin-4(5H)-one |
|---|---|
| Synonyms |
5-{3-[4-(4-Chlorophenyl)-1-piperidinyl]propyl}pyrrolo[1,2-a]quinoxalin-4(5H)-one
Pyrrolo[1,2-a]quinoxalin-4(5H)-one, 5-[3-[4-(4-chlorophenyl)-1-piperidinyl]propyl]- |
| Description | JMS-17-2 is a potent and selective CX3CR1 antagonist with an IC50 of 0.32 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
CX3CR1:0.32 nM (IC50) |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 603.8±55.0 °C at 760 mmHg |
| Molecular Formula | C25H26ClN3O |
| Molecular Weight | 419.95 |
| Flash Point | 319.0±31.5 °C |
| Exact Mass | 419.176453 |
| LogP | 4.80 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.661 |