2-(Azido-PEG3-amido)-1,3-bis(NHS ester)

Modify Date: 2024-01-23 23:59:18

2-(Azido-PEG3-amido)-1,3-bis(NHS ester) structure	Common Name	2-(Azido-PEG3-amido)-1,3-bis(NHS ester)
	CAS Number	2320560-36-7	Molecular Weight	658.61
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₃₈N₆O₁₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2-(Azido-PEG3-amido)-1,3-bis(NHS ester)

2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-(Azido-PEG3-amido)-1,3-bis(NHS ester)

Description	2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₆H₃₈N₆O₁₄
Molecular Weight	658.61

Hazard Codes	Xi