2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane

Modify Date: 2025-09-29 10:50:17

2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane structure	Common Name	2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane
	CAS Number	2086689-05-4	Molecular Weight	464.467
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₃₂N₄O₁₀	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane

2-Azido-PEG3-amido-13-biscarboxylethoxypropane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	1-Azido-14-[(2-carboxyethoxy)methyl]-12-oxo-3,6,9,16-tetraoxa-13-azanonadecan-19-oic acid
Synonym	More Synonyms

Description	2-Azido-PEG3-amido-13-biscarboxylethoxypropane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₈H₃₂N₄O₁₀
Molecular Weight	464.467
Exact Mass	464.211853
LogP	-1.20
InChIKey	NIEBYMXGDWQDQN-UHFFFAOYSA-N
SMILES	[N-]=[N+]=NCCOCCOCCOCCC(=O)NC(COCCC(=O)O)COCCC(=O)O

3,6,9,16-Tetraoxa-13-azanonadecan-19-oic acid, 1-azido-14-[(2-carboxyethoxy)methyl]-12-oxo-

1-Azido-14-[(2-carboxyethoxy)methyl]-12-oxo-3,6,9,16-tetraoxa-13-azanonadecan-19-oic acid

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