VH 101, phenol

Modify Date: 2024-01-14 15:26:10

VH 101, phenol Structure
VH 101, phenol structure
Common Name VH 101, phenol
CAS Number 2306193-99-5 Molecular Weight 532.63
Density N/A Boiling Point N/A
Molecular Formula C26H33FN4O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of VH 101, phenol


E3 ligase Ligand 19 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 19 can be connected to the ligand for protein (e.g., SMARCA BD ligand) by a linker to form PROTACs (e.g., PROTAC 1). PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4[1]。

 Names

Name E3 ligase Ligand 19
Synonym More Synonyms

 VH 101, phenol Biological Activity

Description E3 ligase Ligand 19 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 19 can be connected to the ligand for protein (e.g., SMARCA BD ligand) by a linker to form PROTACs (e.g., PROTAC 1). PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4[1]。
Related Catalog
Target

VHL

References

[1]. Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680.

 Chemical & Physical Properties

Molecular Formula C26H33FN4O5S
Molecular Weight 532.63

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD32201089