Mtb-IN-4

Modify Date: 2024-10-05 16:57:32

Mtb-IN-4 structure	Common Name	Mtb-IN-4
	CAS Number	2306039-13-2	Molecular Weight	430.48
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₁₈N₂O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Mtb-IN-4

Mtb-IN-4 (compound 17h) is a nontoxic isoxazole, with anti-Mycobacterium tuberculosis (Mtb) activity (IC50=0.70 μM). Mtb-IN-4 inhibits Mtb respiration and biofilm formation in macrophage, and enhances antibiotic isoniazid (INH) inhibition against INH-resistant Mtb mutant[1].

Name	Mtb-IN-4

Description	Mtb-IN-4 (compound 17h) is a nontoxic isoxazole, with anti-Mycobacterium tuberculosis (Mtb) activity (IC50=0.70 μM). Mtb-IN-4 inhibits Mtb respiration and biofilm formation in macrophage, and enhances antibiotic isoniazid (INH) inhibition against INH-resistant Mtb mutant[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	Mycobacterium tuberculosis (Mtb)[1]
References	[1]. Sarkar S, et al. Design, Synthesis, and Evaluation of Novel Δ2-Thiazolino 2-Pyridone Derivatives That Potentiate Isoniazid Activity in an Isoniazid-Resistant Mycobacterium tuberculosis Mutant. J Med Chem. 2023 Aug 24;66(16):11056-11077.

Molecular Formula	C₂₄H₁₈N₂O₄S
Molecular Weight	430.48

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Mtb-IN-4

Use of Mtb-IN-4

Names

Mtb-IN-4 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.