FLT3-IN-4

Modify Date: 2024-01-12 11:57:35

FLT3-IN-4 structure	Common Name	FLT3-IN-4
	CAS Number	2304799-09-3	Molecular Weight	431.49
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₅N₇O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FLT3-IN-4

FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor for treating acute myelogenous leukemia[1].

Name	FLT3-IN-4

Description	FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor for treating acute myelogenous leukemia[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FLT3
In Vitro	FLT3-IN-4 (Compound 9u) shows potent inhibitory activities against MV4-11 and Molm-13 cells with IC50 values are 0.089±0.001 nM and 0.022±0.003 nM, respectively[1].
References	[1]. Yuan X, et al. Identification of Pyrrolo[2,3- d]pyrimidine-Based Derivatives as Potent and Orally Effective Fms-like Tyrosine Receptor Kinase 3 (FLT3) Inhibitors for Treating Acute Myelogenous Leukemia. J Med Chem. 2019 Apr 25;62(8):4158-4173.

Molecular Formula	C₂₃H₂₅N₇O₂
Molecular Weight	431.49
Storage condition	-20°C

Hazard Codes	Xn

DC Chemicals Limited
China
Product Name: FLT3-IN-4
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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