FLT3-IN-4

Modify Date: 2025-08-27 18:08:44

FLT3-IN-4 Structure
FLT3-IN-4 structure
Common Name FLT3-IN-4
CAS Number 2304799-09-3 Molecular Weight 431.49
Density N/A Boiling Point N/A
Molecular Formula C23H25N7O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FLT3-IN-4


FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor for treating acute myelogenous leukemia[1].

 Names

Name FLT3-IN-4

 FLT3-IN-4 Biological Activity

Description FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor for treating acute myelogenous leukemia[1].
Related Catalog
In Vitro FLT3-IN-4 (Compound 9u) shows potent inhibitory activities against MV4-11 and Molm-13 cells with IC50 values are 0.089±0.001 nM and 0.022±0.003 nM, respectively[1].
References

[1]. Yuan X, et al. Identification of Pyrrolo[2,3- d]pyrimidine-Based Derivatives as Potent and Orally Effective Fms-like Tyrosine Receptor Kinase 3 (FLT3) Inhibitors for Treating Acute Myelogenous Leukemia. J Med Chem. 2019 Apr 25;62(8):4158-4173.

 Chemical & Physical Properties

Molecular Formula C23H25N7O2
Molecular Weight 431.49
Storage condition -20°C

 Safety Information

Hazard Codes Xn
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