SD 2590 hydrochloride

Modify Date: 2024-01-12 18:07:02

SD 2590 hydrochloride Structure
SD 2590 hydrochloride structure
Common Name SD 2590 hydrochloride
CAS Number 226395-93-3 Molecular Weight 554.96
Density N/A Boiling Point N/A
Molecular Formula C22H26ClF3N2O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SD 2590 hydrochloride


SD-2590 hydrochloride is a potent MMP inhibitor with IC50 values of ﹤0.1, ﹤0.1, 0.18, and 1.7 nM for MMP2, MMP13, MMP9, and MMP8, respectively. SD-2590 hydrochloride inhibits dilation of the left ventricle in rats[1].

 Names

Name SD 2590 (hydrochloride)
Synonym More Synonyms

 SD 2590 hydrochloride Biological Activity

Description SD-2590 hydrochloride is a potent MMP inhibitor with IC50 values of ﹤0.1, ﹤0.1, 0.18, and 1.7 nM for MMP2, MMP13, MMP9, and MMP8, respectively. SD-2590 hydrochloride inhibits dilation of the left ventricle in rats[1].
Related Catalog
References

[1]. Becker DP, et, al. Orally active MMP-1 sparing α-tetrahydropyranyl and α-piperidinyl sulfone matrix metalloproteinase (MMP) inhibitors with efficacy in cancer, arthritis, and cardiovascular disease. J Med Chem. 2010 Sep 23;53(18):6653-80.  

 Chemical & Physical Properties

Molecular Formula C22H26ClF3N2O7S
Molecular Weight 554.96
Exact Mass 554.110107

 Synonyms

MFCD30182243
N-Hydroxy-1-(2-methoxyethyl)-4-({4-[4-(trifluoromethoxy)phenoxy]phenyl}sulfonyl)-4-piperidinecarboxamide hydrochloride (1:1)
4-Piperidinecarboxamide, N-hydroxy-1-(2-methoxyethyl)-4-[[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonyl]-, hydrochloride (1:1)
SD 2590 (hydrochloride)