Cathepsin Inhibitor 1

Modify Date: 2024-01-11 10:40:21

Cathepsin Inhibitor 1 Structure
Cathepsin Inhibitor 1 structure
Common Name Cathepsin Inhibitor 1
CAS Number 225120-65-0 Molecular Weight 401.89000
Density 1.23±0.1 g/cm3 (20 ºC 760 Torr) Boiling Point N/A
Molecular Formula C20H24ClN5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cathepsin Inhibitor 1


Cathepsin inhibitor 1 (compound 25) is a potent and selective inhibitor of Cathepsin, with pIC50s of 7.9, 6.7, 6.0, 5.5 and 5.2 for CatL, CatL2, CatS, CatK, and CatB, respectively[1].

 Names

Name 3-Chloro-N-(cyanomethyl)-Nα-{[1-methyl-3-(2-methyl-2-propanyl)-1H -pyrazol-5-yl]carbonyl}-L-phenylalaninamide
Synonym More Synonyms

 Cathepsin Inhibitor 1 Biological Activity

Description Cathepsin inhibitor 1 (compound 25) is a potent and selective inhibitor of Cathepsin, with pIC50s of 7.9, 6.7, 6.0, 5.5 and 5.2 for CatL, CatL2, CatS, CatK, and CatB, respectively[1].
Related Catalog
References

[1]. Asaad N, et, al. Dipeptidyl nitrile inhibitors of Cathepsin L. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4280-3.

 Chemical & Physical Properties

Density 1.23±0.1 g/cm3 (20 ºC 760 Torr)
Molecular Formula C20H24ClN5O2
Molecular Weight 401.89000
Exact Mass 401.16200
PSA 106.79000
LogP 3.76698
Storage condition -20℃

 Safety Information

HS Code 29242990

 Synonyms

Cathepsin Inhibitor 1