B 973B

Modify Date: 2024-01-08 18:19:33

B 973B Structure
B 973B structure
Common Name B 973B
CAS Number 2244989-34-0 Molecular Weight 452.50
Density N/A Boiling Point N/A
Molecular Formula C24H26F2N6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of B 973B


(-)-(S)-B-973B is a potent allosteric agonism and positive allosteric modulation (ago-PAM) for α7 nAChR, with antinociceptive activity[1].

 Names

Name (-)-(S)-B-973B

 B 973B Biological Activity

Description (-)-(S)-B-973B is a potent allosteric agonism and positive allosteric modulation (ago-PAM) for α7 nAChR, with antinociceptive activity[1].
Related Catalog
Target

α7 nAChR[1]

References

[1]. Garai S, et al. B-973, a Novel α7 nAChR Ago-PAM: Racemic and Asymmetric Synthesis, Electrophysiological Studies, and in Vivo Evaluation. ACS Med Chem Lett. 2018 Oct 11;9(11):1144-1148.

 Chemical & Physical Properties

Molecular Formula C24H26F2N6O
Molecular Weight 452.50