MptpB-IN-1

Modify Date: 2025-08-25 19:55:05

MptpB-IN-1 structure	Common Name	MptpB-IN-1
	CAS Number	2244622-44-2	Molecular Weight	364.18
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₁Cl₂NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MptpB-IN-1

MptpB-IN-1 (Compound 13) is a potent and orally active inhibitor of MptpB. Mycobacterium tuberculosis protein-tyrosine-phosphatase B (MptpB) is a secreted virulence factor that subverts antimicrobial activity in the host. MptpB-IN-1 reduces multidrug-resistant mycobacterium tuberculosis survival and infection burden[1].

Name	MptpB-IN-1

Description	MptpB-IN-1 (Compound 13) is a potent and orally active inhibitor of MptpB. Mycobacterium tuberculosis protein-tyrosine-phosphatase B (MptpB) is a secreted virulence factor that subverts antimicrobial activity in the host. MptpB-IN-1 reduces multidrug-resistant mycobacterium tuberculosis survival and infection burden[1].
Related Catalog	Research Areas >> Infection
References	[1]. Vickers CF, et al. Structure-Based Design of MptpB Inhibitors That Reduce Multidrug-Resistant Mycobacterium tuberculosis Survival and Infection Burden in Vivo. J Med Chem. 2018;61(18):8337-8352.

Molecular Formula	C₁₇H₁₁Cl₂NO₄
Molecular Weight	364.18
InChIKey	RHLHXHOGVCAPFR-UHFFFAOYSA-N
SMILES	Cc1onc(C(=O)O)c1-c1cccc(-c2cc(Cl)c(O)c(Cl)c2)c1

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MptpB-IN-1

Use of MptpB-IN-1

Names

MptpB-IN-1 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.