αvβ1 integrin-IN-2

Modify Date: 2024-02-10 13:04:15

αvβ1 integrin-IN-2 Structure
αvβ1 integrin-IN-2 structure
Common Name αvβ1 integrin-IN-2
CAS Number 2234874-68-9 Molecular Weight 506.64
Density N/A Boiling Point N/A
Molecular Formula C29H38N4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of αvβ1 integrin-IN-2


αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of integrins ανβ1 and α5β1 with IC50s of 0.9 nM,and 33 nM,respectively. αvβ1 integrin-IN-2 also inhibits other integrins with ,,IC50s of 380 nM (ανβ3),280 nM (ανβ5),230 nM (ανβ6),87 nM (ανβ8),respectively,in SPRA assay[1].

 Names

Name αvβ1 integrin-IN-2

 αvβ1 integrin-IN-2 Biological Activity

Description αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of integrins ανβ1 and α5β1 with IC50s of 0.9 nM,and 33 nM,respectively. αvβ1 integrin-IN-2 also inhibits other integrins with ,,IC50s of 380 nM (ανβ3),280 nM (ανβ5),230 nM (ανβ6),87 nM (ανβ8),respectively,in SPRA assay[1].
Related Catalog
References

[1]. Ruminski PG, et al. Preparation of ((tetrahydronaphthyridinylethoxy)pyrazolyl) butanoic acid as integrin antagonists for the treatment and prevention of diseases. World Intellectual Property Organization, WO2018132268 A1. 2018-07-19.

 Chemical & Physical Properties

Molecular Formula C29H38N4O4
Molecular Weight 506.64