2234874-68-9

2234874-68-9 structure
2234874-68-9 structure
  • Name: αvβ1 integrin-IN-2
  • Chemical Name: αvβ1 integrin-IN-2
  • CAS Number: 2234874-68-9
  • Molecular Formula: C29H38N4O4
  • Molecular Weight: 506.64
  • Catalog: Signaling Pathways Cytoskeleton Integrin
  • Create Date: 2023-10-02 10:37:23
  • Modify Date: 2024-02-10 13:04:15
  • αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of integrins ανβ1 and α5β1 with IC50s of 0.9 nM,and 33 nM,respectively. αvβ1 integrin-IN-2 also inhibits other integrins with ,,IC50s of 380 nM (ανβ3),280 nM (ανβ5),230 nM (ανβ6),87 nM (ανβ8),respectively,in SPRA assay[1].

Name αvβ1 integrin-IN-2
Description αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of integrins ανβ1 and α5β1 with IC50s of 0.9 nM,and 33 nM,respectively. αvβ1 integrin-IN-2 also inhibits other integrins with ,,IC50s of 380 nM (ανβ3),280 nM (ανβ5),230 nM (ανβ6),87 nM (ανβ8),respectively,in SPRA assay[1].
Related Catalog
References

[1]. Ruminski PG, et al. Preparation of ((tetrahydronaphthyridinylethoxy)pyrazolyl) butanoic acid as integrin antagonists for the treatment and prevention of diseases. World Intellectual Property Organization, WO2018132268 A1. 2018-07-19.

Molecular Formula C29H38N4O4
Molecular Weight 506.64