SHR1653

Modify Date: 2024-01-16 08:31:44

SHR1653 Structure
SHR1653 structure
Common Name SHR1653
CAS Number 2231770-73-1 Molecular Weight 429.88
Density N/A Boiling Point N/A
Molecular Formula C21H21ClFN5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SHR1653


SHR1653 is a highly potent, selective and brain penetrated oxytocin receptor (OTR) antagonist, with an IC50 of 15 nM for hOTR[1].

 Names

Name SHR1653

 SHR1653 Biological Activity

Description SHR1653 is a highly potent, selective and brain penetrated oxytocin receptor (OTR) antagonist, with an IC50 of 15 nM for hOTR[1].
Related Catalog
Target

IC50: 15 nM (hOTR)[1].

References

[1]. Li X, et al. Discovery of SHR1653, a Highly Potent and Selective OTR Antagonist with Improved Blood-Brain Barrier Penetration. ACS Med Chem Lett. 2019 May 29;10(6):996-1001.

 Chemical & Physical Properties

Molecular Formula C21H21ClFN5O2
Molecular Weight 429.88
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