Shanghai Nianxing Industrial Co., Ltd
China
Product Name: SHR1653
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2231770-73-1

2231770-73-1 structure

2231770-73-1 structure

Name: SHR1653
Chemical Name: SHR1653
CAS Number: 2231770-73-1
Molecular Formula: C₂₁H₂₁ClFN₅O₂
Molecular Weight: 429.88
Catalog: Signaling Pathways GPCR/G Protein Oxytocin Receptor
Create Date: 2019-08-04 08:14:58
Modify Date: 2025-08-26 20:27:16
SHR1653 is a highly potent, selective and brain penetrated oxytocin receptor (OTR) antagonist, with an IC50 of 15 nM for hOTR[1].

Name	SHR1653

Description	SHR1653 is a highly potent, selective and brain penetrated oxytocin receptor (OTR) antagonist, with an IC50 of 15 nM for hOTR[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Oxytocin Receptor Research Areas >> Neurological Disease
Target	IC50: 15 nM (hOTR)[1].
References	[1]. Li X, et al. Discovery of SHR1653, a Highly Potent and Selective OTR Antagonist with Improved Blood-Brain Barrier Penetration. ACS Med Chem Lett. 2019 May 29;10(6):996-1001.

Molecular Formula	C₂₁H₂₁ClFN₅O₂
Molecular Weight	429.88

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