3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine
Modify Date: 2024-01-13 06:14:56
3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine structure
|
Common Name | 3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine | ||
|---|---|---|---|---|
| CAS Number | 2226941-29-1 | Molecular Weight | 480.51 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H24N4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine (Compound 7) is an inhibitor of protein kinases, with IC50s of 0.092, 0.26, 0.77 μM for PKC-α, ROCK, ASK1. 3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine shows potent cytotoxicity against PC-3 cancer cells with an IC50 value of 0.16 μM[1]. |
| Name | 3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine |
|---|
| Description | 3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine (Compound 7) is an inhibitor of protein kinases, with IC50s of 0.092, 0.26, 0.77 μM for PKC-α, ROCK, ASK1. 3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine shows potent cytotoxicity against PC-3 cancer cells with an IC50 value of 0.16 μM[1]. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C28H24N4O4 |
|---|---|
| Molecular Weight | 480.51 |