7-Aminodeacetoxycephalosporanic acid
7-Aminodeacetoxycephalosporanic acid structure
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Common Name | 7-Aminodeacetoxycephalosporanic acid | ||
|---|---|---|---|---|
| CAS Number | 22252-43-3 | Molecular Weight | 214.242 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 517.6±50.0 °C at 760 mmHg | |
| Molecular Formula | C8H10N2O3S | Melting Point | 234ºC (dec.) | |
| MSDS | Chinese USA | Flash Point | 266.8±30.1 °C | |
| Symbol |
GHS08 |
Signal Word | Danger | |
Use of 7-Aminodeacetoxycephalosporanic acid7-Aminodeacetoxycephalosporanic acid (7-ADCA) is a key intermediate in the synthesis of cephalosporins[1]. |
| Name | 7β-aminodeacetoxycephalosporanic acid |
|---|---|
| Synonym | More Synonyms |
| Description | 7-Aminodeacetoxycephalosporanic acid (7-ADCA) is a key intermediate in the synthesis of cephalosporins[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 517.6±50.0 °C at 760 mmHg |
| Melting Point | 234ºC (dec.) |
| Molecular Formula | C8H10N2O3S |
| Molecular Weight | 214.242 |
| Flash Point | 266.8±30.1 °C |
| Exact Mass | 214.041214 |
| PSA | 108.93000 |
| LogP | -0.81 |
| Vapour Pressure | 0.0±2.9 mmHg at 25°C |
| Index of Refraction | 1.698 |
| Storage condition | 2-8°C |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Symbol |
GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H317-H334 |
| Precautionary Statements | P261-P280-P342 + P311 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R42/43 |
| Safety Phrases | S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| Precursor 0 | |
|---|---|
| DownStream 9 | |
![(6R,7R)-3-methyl-8-oxo-7-[(1-phenylcyclopentanecarbonyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid structure](https://www.chemsrc.com/caspic/410/108098-25-5.png)
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Enhanced enzymatic synthesis of a semi-synthetic cephalosprin, cefaclor, with in situ product removal.
Biotechnol. Lett. 25(14) , 1195-8, (2003) In the enzymatic synthesis of cefaclor, 3-chloro-7-d-(2-phenylglycinamide)-3-cephem-4-carboxylic acid, from phenylglycine methyl ester and 7-aminodesacetoxymethyl-3-chlorocephalosporanic acid, the in ... |
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Enzymatic production of cephalexin.
Enzyme Microb. Technol. 16(8) , 715-8, (1994) Enzymatic production of cephalexin using immobilized penicillin G acylase was studied. The factors that affect the conversion of 7-amino-3-deacetoxycephalosporanic acid (7-ADCA) to cephalexin, such as... |
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Continuous cultivations of a Penicillium chrysogenum strain expressing the expandase gene from Streptomyces clavuligerus: Kinetics of adipoyl-7-aminodeacetoxycephalosporanic acid and byproduct formations.
Biotechnol. Bioeng. 83(3) , 353-60, (2003) The production kinetics of a transformed strain of Penicillium chrysogenum expressing the expandase gene from Streptomyces clavuligerus was investigated in chemostat cultivations. The recombinant stra... |
| Cefadroxil Related Compound B |
| (6R,7R)-7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| MFCD00151456 |
| EINECS 244-870-1 |
| 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-methyl-8-oxo-, (6R,7R)- |
| 7beta-aminodeacetoxycephalosporanic acid |
| 7-Aminodesacetoxycephalosporanic acid |
| 7-ADCA |
| Cefalexin Impurity 2 |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 7-Aminodeacetoxycephalosporanic acid
- Price: ￥158.0/5g ￥428.0/25g
- Purity: 98.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: 7-Aminodeacetoxycephalosporanic acid
- Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 7-Amino desacetoxy cephalosporanic acid
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: 7-Amino-3-methyl-3-cephem-4-carboxylic acid
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: 7-Amino-deacetoxycephalosporanic acid (7-ADCA)
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
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