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22252-43-3

22252-43-3 structure
22252-43-3 structure
  • Name: 7-Aminodeacetoxycephalosporanic acid
  • Chemical Name: 7β-aminodeacetoxycephalosporanic acid
  • CAS Number: 22252-43-3
  • Molecular Formula: C8H10N2O3S
  • Molecular Weight: 214.242
  • Catalog: Research Areas Others
  • Create Date: 2018-06-27 08:55:43
  • Modify Date: 2024-01-02 22:25:13
  • 7-Aminodeacetoxycephalosporanic acid (7-ADCA) is a key intermediate in the synthesis of cephalosporins[1].

Name 7β-aminodeacetoxycephalosporanic acid
Synonyms Cefadroxil Related Compound B
(6R,7R)-7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
MFCD00151456
EINECS 244-870-1
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-methyl-8-oxo-, (6R,7R)-
7beta-aminodeacetoxycephalosporanic acid
7-Aminodesacetoxycephalosporanic acid
7-ADCA
Cefalexin Impurity 2
Description 7-Aminodeacetoxycephalosporanic acid (7-ADCA) is a key intermediate in the synthesis of cephalosporins[1].
Related Catalog
References

[1]. Linda G Otten, et al. Mutational Analysis of a Key Residue in the Substrate Specificity of a Cephalosporin Acylase. Chembiochem. 2004 Jun 7;5(6):820-5.

Density 1.6±0.1 g/cm3
Boiling Point 517.6±50.0 °C at 760 mmHg
Melting Point 234ºC (dec.)
Molecular Formula C8H10N2O3S
Molecular Weight 214.242
Flash Point 266.8±30.1 °C
Exact Mass 214.041214
PSA 108.93000
LogP -0.81
Vapour Pressure 0.0±2.9 mmHg at 25°C
Index of Refraction 1.698
Storage condition 2-8°C
Stability Stable. Incompatible with strong oxidizing agents.
Symbol GHS08
GHS08
Signal Word Danger
Hazard Statements H317-H334
Precautionary Statements P261-P280-P342 + P311
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R42/43
Safety Phrases S36
RIDADR NONH for all modes of transport
WGK Germany 3