Bm-MPK1-IN-15b

Modify Date: 2023-03-03 21:07:27

Bm-MPK1-IN-15b structure	Common Name	Bm-MPK1-IN-15b
	CAS Number	2222294-62-2	Molecular Weight	391.475
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₅N₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Bm-MPK1-IN-15b

Bm-MPK1-IN-15b is a potent, orally bioavailable inhibitor of B. malayi stress-activated kinase Bm-MPK1 with IC50 of 24 nM; inhibits human p38α and JNK3 with IC50 of 26 and 170 nM, respectively; reduces the motility of adult worms at 100 nM, Bm-MPK1-IN-15b is a tool compound for in vivo studies aimed at strengthening the role of Bm MPK1 in B. malayi response to host oxidative stress.

Name	Bm-MPK1-IN-15b

Description	Bm-MPK1-IN-15b is a potent, orally bioavailable inhibitor of B. malayi stress-activated kinase Bm-MPK1 with IC50 of 24 nM; inhibits human p38α and JNK3 with IC50 of 26 and 170 nM, respectively; reduces the motility of adult worms at 100 nM, Bm-MPK1-IN-15b is a tool compound for in vivo studies aimed at strengthening the role of Bm MPK1 in B. malayi response to host oxidative stress.
References	References 1. Tummalapalli SR, et al. ACS Med Chem Lett. 2018 Feb 9;9(3):210-214. View Related Products by Target Parasite

Molecular Formula	C₂₂H₂₅N₅O₂
Molecular Weight	391.475

DC Chemicals Limited
China
Product Name: Bm-MPK1-IN-15b
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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