Amycolatopsin A

Modify Date: 2025-08-25 17:55:45

Amycolatopsin A Structure
Amycolatopsin A structure
Common Name Amycolatopsin A
CAS Number 2209112-96-7 Molecular Weight 1187.41
Density N/A Boiling Point N/A
Molecular Formula C60H98O23 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amycolatopsin A


Amycolatopsin A is a 20-membered macrolide, that can be isolated from a strain of the rare actinomycete Amycolatopsis sp. MST‐108494. Amycolatopsin A shows antimycobacterial activity against Mycobacterium bovis (BCG) and M. tuberculosis (H37Rv) with IC50 values of 0.4 µM and 4.4 µM, respectively[1].

 Names

Name Amycolatopsin A

 Amycolatopsin A Biological Activity

Description Amycolatopsin A is a 20-membered macrolide, that can be isolated from a strain of the rare actinomycete Amycolatopsis sp. MST‐108494. Amycolatopsin A shows antimycobacterial activity against Mycobacterium bovis (BCG) and M. tuberculosis (H37Rv) with IC50 values of 0.4 µM and 4.4 µM, respectively[1].
Related Catalog
In Vitro Amycolatopsin A 对人结肠癌 (SW620) 和肺癌 (NCIH-460) 细胞系具有显著的细胞毒性,IC50 值分别为 0.08 µM 和 1.2 µM[1]。
References

[1]. Al-Fadhli AA, et al. Macrolides from rare actinomycetes: Structures and bioactivities. Int J Antimicrob Agents. 2022 Feb;59(2):106523.  

 Chemical & Physical Properties

Molecular Formula C60H98O23
Molecular Weight 1187.41
InChIKey VGMCXRHEZZYRBZ-NPMLRHTESA-N
SMILES COCCCC1OC(O)(C(C)C2CC(OC)C(O)C=C(C)C=C(C)C=C(C)C(OC3OC(C)C(OC)C(O)C3O)C(C)C=C(CO)C=C(OC)C=C(C)C(=O)O2)C(OC)C(O)C1(C)OC1CC(O)C(OC2CC(C)(O)C(O)C(C)O2)C(C)O1
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