Amycolatopsin A

Names

[ CAS No. ]:
2209112-96-7

[ Name ]:
Amycolatopsin A

Biological Activity

[Description]:

Amycolatopsin A is a 20-membered macrolide, that can be isolated from a strain of the rare actinomycete Amycolatopsis sp. MST‐108494. Amycolatopsin A shows antimycobacterial activity against Mycobacterium bovis (BCG) and M. tuberculosis (H37Rv) with IC50 values of 0.4 µM and 4.4 µM, respectively[1].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Amycolatopsin A 对人结肠癌 (SW620) 和肺癌 (NCIH-460) 细胞系具有显著的细胞毒性，IC50 值分别为 0.08 µM 和 1.2 µM[1]。

[References]

[1]. Al-Fadhli AA, et al. Macrolides from rare actinomycetes: Structures and bioactivities. Int J Antimicrob Agents. 2022 Feb;59(2):106523.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆₀H₉₈O₂₃

[ Molecular Weight ]:
1187.41

Related Compounds

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