2209112-96-7

2209112-96-7 structure

Name: Amycolatopsin A
Chemical Name: Amycolatopsin A
CAS Number: 2209112-96-7
Molecular Formula: C₆₀H₉₈O₂₃
Molecular Weight: 1187.41
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2023-04-04 12:25:49
Modify Date: 2025-08-25 17:55:45
Amycolatopsin A is a 20-membered macrolide, that can be isolated from a strain of the rare actinomycete Amycolatopsis sp. MST‐108494. Amycolatopsin A shows antimycobacterial activity against Mycobacterium bovis (BCG) and M. tuberculosis (H37Rv) with IC50 values of 0.4 µM and 4.4 µM, respectively[1].

Name	Amycolatopsin A

Description	Amycolatopsin A is a 20-membered macrolide, that can be isolated from a strain of the rare actinomycete Amycolatopsis sp. MST‐108494. Amycolatopsin A shows antimycobacterial activity against Mycobacterium bovis (BCG) and M. tuberculosis (H37Rv) with IC50 values of 0.4 µM and 4.4 µM, respectively[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Amycolatopsin A 对人结肠癌 (SW620) 和肺癌 (NCIH-460) 细胞系具有显著的细胞毒性，IC50 值分别为 0.08 µM 和 1.2 µM[1]。
References	[1]. Al-Fadhli AA, et al. Macrolides from rare actinomycetes: Structures and bioactivities. Int J Antimicrob Agents. 2022 Feb;59(2):106523.

Molecular Formula	C₆₀H₉₈O₂₃
Molecular Weight	1187.41