Amidate-VC-PAB-MMAF
Modify Date: 2024-04-06 00:42:36
Amidate-VC-PAB-MMAF structure
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Common Name | Amidate-VC-PAB-MMAF | ||
|---|---|---|---|---|
| CAS Number | 2202782-90-7 | Molecular Weight | 1372.59 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C69H102N11O16P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Amidate-VC-PAB-MMAFAmidate-VC-PAB-MMAF consists a cleavable ADC linker (Amidate-VC-PAB) and a potent tubulin polymerization inhibitor (MMAF). Amidate-VC-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs). Amidate-VC-PAB-MMAF reduces off-target cytotoxicity of ADCs[1]. |
| Name | Amidate-VC-PAB-MMAF |
|---|
| Description | Amidate-VC-PAB-MMAF consists a cleavable ADC linker (Amidate-VC-PAB) and a potent tubulin polymerization inhibitor (MMAF). Amidate-VC-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs). Amidate-VC-PAB-MMAF reduces off-target cytotoxicity of ADCs[1]. |
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| Related Catalog | |
| References |
[1]. Nareshkumar Jain, et al. Current ADC Linker Chemistry. Pharm Res. 2015 Nov;32(11):3526-40. |
| Molecular Formula | C69H102N11O16P |
|---|---|
| Molecular Weight | 1372.59 |