Amidate-VC-PAB-MMAF

Modify Date: 2024-04-06 00:42:36

Amidate-VC-PAB-MMAF Structure
Amidate-VC-PAB-MMAF structure
Common Name Amidate-VC-PAB-MMAF
CAS Number 2202782-90-7 Molecular Weight 1372.59
Density N/A Boiling Point N/A
Molecular Formula C69H102N11O16P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amidate-VC-PAB-MMAF


Amidate-VC-PAB-MMAF consists a cleavable ADC linker (Amidate-VC-PAB) and a potent tubulin polymerization inhibitor (MMAF). Amidate-VC-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs). Amidate-VC-PAB-MMAF reduces off-target cytotoxicity of ADCs[1].

 Names

Name Amidate-VC-PAB-MMAF

 Amidate-VC-PAB-MMAF Biological Activity

Description Amidate-VC-PAB-MMAF consists a cleavable ADC linker (Amidate-VC-PAB) and a potent tubulin polymerization inhibitor (MMAF). Amidate-VC-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs). Amidate-VC-PAB-MMAF reduces off-target cytotoxicity of ADCs[1].
Related Catalog
References

[1]. Nareshkumar Jain, et al. Current ADC Linker Chemistry. Pharm Res. 2015 Nov;32(11):3526-40.

 Chemical & Physical Properties

Molecular Formula C69H102N11O16P
Molecular Weight 1372.59
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