2202782-90-7
2202782-90-7 structure
- Name: Amidate-VC-PAB-MMAF
- Chemical Name: Amidate-VC-PAB-MMAF
- CAS Number: 2202782-90-7
- Molecular Formula: C69H102N11O16P
- Molecular Weight: 1372.59
- Catalog: Research Areas Cancer
- Create Date: 2022-08-11 19:38:45
- Modify Date: 2024-04-06 00:42:36
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Amidate-VC-PAB-MMAF consists a cleavable ADC linker (Amidate-VC-PAB) and a potent tubulin polymerization inhibitor (MMAF). Amidate-VC-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs). Amidate-VC-PAB-MMAF reduces off-target cytotoxicity of ADCs[1].
| Name | Amidate-VC-PAB-MMAF |
|---|
| Description | Amidate-VC-PAB-MMAF consists a cleavable ADC linker (Amidate-VC-PAB) and a potent tubulin polymerization inhibitor (MMAF). Amidate-VC-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs). Amidate-VC-PAB-MMAF reduces off-target cytotoxicity of ADCs[1]. |
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| Related Catalog | |
| References |
[1]. Nareshkumar Jain, et al. Current ADC Linker Chemistry. Pharm Res. 2015 Nov;32(11):3526-40. |
| Molecular Formula | C69H102N11O16P |
|---|---|
| Molecular Weight | 1372.59 |