Griffipavixanthone

Modify Date: 2024-01-10 19:25:40

Griffipavixanthone Structure
Griffipavixanthone structure
Common Name Griffipavixanthone
CAS Number 219649-95-3 Molecular Weight 652.60
Density 1.6±0.1 g/cm3 Boiling Point 862.8±65.0 °C at 760 mmHg
Molecular Formula C36H28O12 Melting Point N/A
MSDS N/A Flash Point 277.7±27.8 °C

 Use of Griffipavixanthone


Griffipavixanthone can be extracted from Garcinia schomburgkiana. Griffipavixanthone induces cell apoptosis through mitochondrial apoptotic pathway accompanying with ROS production. Griffipavixanthone is an anti-cancer agent. Griffipavixanthone is a weak sucrase inhibitor (IC50: 4.58 mM)[1][2][3].

 Names

Name (8S,8aS,12aR)-1,3,6,7-Tetrahydroxy-9,9,11-trimethyl-8-(3,4,6,8-te trahydroxy-9-oxo-9H-xanthen-1-yl)-8a,9,10,12a-tetrahydroindeno[1, 2-a]xanthen-13(8H)-one
Synonym More Synonyms

 Griffipavixanthone Biological Activity

Description Griffipavixanthone can be extracted from Garcinia schomburgkiana. Griffipavixanthone induces cell apoptosis through mitochondrial apoptotic pathway accompanying with ROS production. Griffipavixanthone is an anti-cancer agent. Griffipavixanthone is a weak sucrase inhibitor (IC50: 4.58 mM)[1][2][3].
Related Catalog
References

[1]. Lien Do TM, et al. Schomburgkixanthone, a novel bixanthone from the twigs of Garcinia schomburgkiana. Nat Prod Res. 2021 Nov;35(21):3613-3618.  

[2]. Shi JM, et al. Griffipavixanthone from Garcinia oblongifolia champ induces cell apoptosis in human non-small-cell lung cancer H520 cells in vitro. Molecules. 2014 Jan 27;19(2):1422-31.  

[3]. Ma Y, et al. Griffipavixanthone induces apoptosis of human breast cancer MCF-7 cells in vitro. Breast Cancer. 2019 Mar;26(2):190-197.  

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 862.8±65.0 °C at 760 mmHg
Molecular Formula C36H28O12
Molecular Weight 652.60
Flash Point 277.7±27.8 °C
Exact Mass 652.158081
PSA 222.26000
LogP 4.32
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.772

 Safety Information

Hazard Codes Xi

 Synonyms

(8S,8aS,12aR)-1,3,6,7-Tetrahydroxy-9,9,11-trimethyl-8-(3,4,6,8-tetrahydroxy-9-oxo-9H-xanthen-1-yl)-8a,9,10,12a-tetrahydroindeno[1,2-a]xanthen-13(8H)-one
Indeno[1,2-a]xanthen-13(8H)-one, 8a,9,10,12a-tetrahydro-1,3,6,7-tetrahydroxy-9,9,11-trimethyl-8-(3,4,6,8-tetrahydroxy-9-oxo-9H-xanthen-1-yl)-, (8S,8aS,12aR)-
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