AGH-192

Modify Date: 2024-04-07 01:19:23

AGH-192 Structure
AGH-192 structure
Common Name AGH-192
CAS Number 2173387-57-8 Molecular Weight 355.155
Density N/A Boiling Point N/A
Molecular Formula C13H11FIn3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AGH-192


AGH-192 is a potent, selective, orally bioavailable 5-HT7 receptor agonist with Ki of 4 nM.AGH-192 displays excellent water solubility, high selectivity over related CNS targets, high metabolic stability, oral bioavailability and low cytotoxicity.AGH-192 could crosses blood-brain barrier to a high extent.AGH-192 alleviates the symptoms of neuropathic pain in a mouse model.

 Names

Name AGH-192

 AGH-192 Biological Activity

Description AGH-192 is a potent, selective, orally bioavailable 5-HT7 receptor agonist with Ki of 4 nM.AGH-192 displays excellent water solubility, high selectivity over related CNS targets, high metabolic stability, oral bioavailability and low cytotoxicity.AGH-192 could crosses blood-brain barrier to a high extent.AGH-192 alleviates the symptoms of neuropathic pain in a mouse model.
References 1. Adam S Hogendorf, et al. Eur J Med Chem. 2019 May 15;170:261-275.

 Chemical & Physical Properties

Molecular Formula C13H11FIn3
Molecular Weight 355.155
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