2173387-57-8
2173387-57-8 structure
- Name: AGH-192
- Chemical Name: AGH-192
- CAS Number: 2173387-57-8
- Molecular Formula: C13H11FIn3
- Molecular Weight: 355.155
- Create Date: 2022-07-10 19:49:36
- Modify Date: 2025-11-21 19:31:09
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AGH-192 is a potent, selective, orally bioavailable 5-HT7 receptor agonist with Ki of 4 nM.AGH-192 displays excellent water solubility, high selectivity over related CNS targets, high metabolic stability, oral bioavailability and low cytotoxicity.AGH-192 could crosses blood-brain barrier to a high extent.AGH-192 alleviates the symptoms of neuropathic pain in a mouse model.
| Name | AGH-192 |
|---|
| Description | AGH-192 is a potent, selective, orally bioavailable 5-HT7 receptor agonist with Ki of 4 nM.AGH-192 displays excellent water solubility, high selectivity over related CNS targets, high metabolic stability, oral bioavailability and low cytotoxicity.AGH-192 could crosses blood-brain barrier to a high extent.AGH-192 alleviates the symptoms of neuropathic pain in a mouse model. |
|---|---|
| References | 1. Adam S Hogendorf, et al. Eur J Med Chem. 2019 May 15;170:261-275. |
| Molecular Formula | C13H11FIn3 |
|---|---|
| Molecular Weight | 355.155 |