LY2794193

Modify Date: 2024-01-30 10:59:27

LY2794193 Structure
LY2794193 structure
Common Name LY2794193
CAS Number 2173037-97-1 Molecular Weight 334.32
Density N/A Boiling Point N/A
Molecular Formula C16H18N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LY2794193


LY2794193 is a highly potent and selective mGlu3 receptor agonist (hmGlu3 Ki=0.927 nM,EC50=0.47 nM; hmGlu2 Ki=412 nM,EC50=47.5 nM)[1].

 Names

Name LY2794193

 LY2794193 Biological Activity

Description LY2794193 is a highly potent and selective mGlu3 receptor agonist (hmGlu3 Ki=0.927 nM,EC50=0.47 nM; hmGlu2 Ki=412 nM,EC50=47.5 nM)[1].
Related Catalog
Target

mGluR3:0.47 nM (EC50)

mGluR3:0.927 nM (Ki)

mGluR2:47.5 (EC50)

mGluR2:412 (Ki)

References

[1]. Monn JA, et al. Synthesis and Pharmacological Characterization of C4β-Amide-Substituted 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1 S,2 S,4 S,5 R,6 S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2794193), a Highly Potent and Selective mGlu3 Receptor Agonist. J Med Chem. 2018 Mar 22;61(6):2303-2328.

 Chemical & Physical Properties

Molecular Formula C16H18N2O6
Molecular Weight 334.32
Storage condition 2-8°C
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