VH032-linker 5

Modify Date: 2024-04-08 22:24:12

VH032-linker 5 Structure
VH032-linker 5 structure
Common Name VH032-linker 5
CAS Number 2172819-74-6 Molecular Weight 558.690
Density 1.3±0.1 g/cm3 Boiling Point 878.5±65.0 °C at 760 mmHg
Molecular Formula C28H38N4O6S Melting Point N/A
MSDS N/A Flash Point 485.1±34.3 °C

 Use of VH032-linker 5


VH032-linker 5 is a derivative of the proteolysis-targeting chimera technology (PROTAC) for PROTAC research and development; by incorporating an E3 ligase ligand and an alkyl C4 linker with terminal carboxylic acid, it is ready for conjugation to a target protein ligand.

 Names

Name N-(5-Carboxypentanoyl)-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 878.5±65.0 °C at 760 mmHg
Molecular Formula C28H38N4O6S
Molecular Weight 558.690
Flash Point 485.1±34.3 °C
Exact Mass 558.251221
LogP 1.17
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.586

 Synonyms

L-Prolinamide, N-(5-carboxy-1-oxopentyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
N-(5-Carboxypentanoyl)-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide