![]() QPX7728 structure
|
Common Name | QPX7728 | ||
---|---|---|---|---|
CAS Number | 2170834-63-4 | Molecular Weight | 221.98 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C10H8BFO4 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of QPX7728QPX7728 is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. QPX7728 inhibits key serine and metallo beta-lactamases at a nano molar range[1]. |
Name | QPX7728 |
---|
Description | QPX7728 is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. QPX7728 inhibits key serine and metallo beta-lactamases at a nano molar range[1]. |
---|---|
Related Catalog | |
In Vitro | QPX7728 is a potent inhibitor of Class D carbapenemases from A. baumannii[1]. QPX7728 is minimally affected by the activity of major MDR efflux pumps from P. aeruginosa, representing a significant improvement over the earlier generation boronate beta-lactamase inhibitor (BLI) vaborbactam[1]. The ultra-broad-spectrum beta-lactamase inhibition profile combined with enhancement of the activity of multiple beta-lactam antibiotics with varying sensitivity to the intrinsic resistance mechanisms of efflux and permeability indicate QPX7728 is a useful inhibitor for use with multiple beta-lactam antibiotics[1]. |
References |
Molecular Formula | C10H8BFO4 |
---|---|
Molecular Weight | 221.98 |