2170848-99-2
2170848-99-2 structure
- Name: QPX7728-OH disodium
- Chemical Name: QPX7728-OH disodium
- CAS Number: 2170848-99-2
- Molecular Formula: C10H6BFNa2O5
- Molecular Weight: 281.94
- Catalog: Signaling Pathways Anti-infection Bacterial
- Create Date: 2020-06-01 11:17:31
- Modify Date: 2024-01-16 06:52:19
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QPX7728-OH disodium (compound 13) is a boronic acid β-lactamase inhibitor, exacted from WO2018005662A1, compound 13. QPX7728-OH disodium inhibits cleavage of Nitrocefin (HY-108913) by purified class A, C and D enzymes, with Kis less than 0.1 µΜ[1].
| Name | QPX7728-OH disodium |
|---|
| Description | QPX7728-OH disodium (compound 13) is a boronic acid β-lactamase inhibitor, exacted from WO2018005662A1, compound 13. QPX7728-OH disodium inhibits cleavage of Nitrocefin (HY-108913) by purified class A, C and D enzymes, with Kis less than 0.1 µΜ[1]. |
|---|---|
| Related Catalog | |
| In Vitro | QPX7728-OH disodium potentiates Aztreonam (HY-B0129) and Tigemonam (HY-U00380) against strains expressing class A and class C enzymes, with MICs≤5 µg/mL. QPX7728-OH disodium potentiates Biapenem (HY-13573) against strains expressing class A (KPC) or class D (OXA-48) carbapenemases, with MICs≤5 µg/mL[1]. |
| References |
[1]. Scott Hecker, et al. Boronic acid derivatives and therapeutic uses thereof. WO2018005662A1. |
| Molecular Formula | C10H6BFNa2O5 |
|---|---|
| Molecular Weight | 281.94 |