2170834-63-4
2170834-63-4 structure
- Name: QPX7728
- Chemical Name: QPX7728
- CAS Number: 2170834-63-4
- Molecular Formula: C10H8BFO4
- Molecular Weight: 221.98
- Catalog: Signaling Pathways Anti-infection Bacterial
- Create Date: 2020-06-01 18:22:36
- Modify Date: 2025-08-24 19:01:06
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QPX7728 is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. QPX7728 inhibits key serine and metallo beta-lactamases at a nano molar range[1].
| Name | QPX7728 |
|---|
| Description | QPX7728 is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. QPX7728 inhibits key serine and metallo beta-lactamases at a nano molar range[1]. |
|---|---|
| Related Catalog | |
| In Vitro | QPX7728 is a potent inhibitor of Class D carbapenemases from A. baumannii[1]. QPX7728 is minimally affected by the activity of major MDR efflux pumps from P. aeruginosa, representing a significant improvement over the earlier generation boronate beta-lactamase inhibitor (BLI) vaborbactam[1]. The ultra-broad-spectrum beta-lactamase inhibition profile combined with enhancement of the activity of multiple beta-lactam antibiotics with varying sensitivity to the intrinsic resistance mechanisms of efflux and permeability indicate QPX7728 is a useful inhibitor for use with multiple beta-lactam antibiotics[1]. |
| References |
| Molecular Formula | C10H8BFO4 |
|---|---|
| Molecular Weight | 221.98 |