USP7-IN-5

Modify Date: 2025-09-11 12:05:36

USP7-IN-5 Structure
USP7-IN-5 structure
Common Name USP7-IN-5
CAS Number 2166599-74-0 Molecular Weight 641.76
Density N/A Boiling Point N/A
Molecular Formula C36H43N5O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of USP7-IN-5


USP7-IN-5 is a potent ubiquitin specific protease 7 (USP7) inhibitor extracted from patent WO2017212012A1, example 40, has an IC50 of 49.9 nM[1].

 Names

Name USP7-IN-5

 USP7-IN-5 Biological Activity

Description USP7-IN-5 is a potent ubiquitin specific protease 7 (USP7) inhibitor extracted from patent WO2017212012A1, example 40, has an IC50 of 49.9 nM[1].
Related Catalog
Target

IC50: 49.9 nM (USP7)[1]

In Vitro USP7-IN-5 (example 40) shows cytotoxicity to MM1S cells, with an IC50 31.5 nM[1].
References

[1]. András Kotschy, et al. New piperidinyl derivatives, a process for their preparation and pharmaceutical compositions containing them. WO2017212012A1.

 Chemical & Physical Properties

Molecular Formula C36H43N5O6
Molecular Weight 641.76
InChIKey QKYAFWNZSJXZFS-DGPALRBDSA-N
SMILES COc1ccc(-n2ccc3c(=O)n(CC4(O)CCN(C(=O)C5CCN(C(=O)OC(C)(C)C)CC5c5ccccc5)CC4)cnc32)cc1
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