2166586-47-4

2166586-47-4 structure

2166586-47-4 structure

Name: USP7-IN-6
Chemical Name: USP7-IN-6
CAS Number: 2166586-47-4
Molecular Formula: C₄₁H₄₃N₇O₄S
Molecular Weight: 729.89
Catalog: Signaling Pathways Cell Cycle/DNA Damage Deubiquitinase
Create Date: 2020-04-05 15:26:02
Modify Date: 2024-01-14 21:18:15
USP7-IN-6 is a potent ubiquitin specific protease 7 (USP7) inhibitor, extracted from patent WO2017212010A1, example 25, has an IC50 of 6.8 nM[1].

Name	USP7-IN-6

Description	USP7-IN-6 is a potent ubiquitin specific protease 7 (USP7) inhibitor, extracted from patent WO2017212010A1, example 25, has an IC50 of 6.8 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Deubiquitinase
Target	IC50: 6.8 nM (USP7)[1]
In Vitro	USP7-IN-6 (example 25) shows cytotoxicity to Z138 tumour cells, with an IC50 1.1 nM[1].
References	[1]. András Kotschy, et al. New (hetero)aryl-substituted-piperidinyl derivatives, a process for their preparation and pharmaceutical compositions containing them. WO2017212010A1.

Molecular Formula	C₄₁H₄₃N₇O₄S
Molecular Weight	729.89