HS-1371
Modify Date: 2025-08-25 18:37:00
HS-1371 structure
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Common Name | HS-1371 | ||
|---|---|---|---|---|
| CAS Number | 2158197-70-5 | Molecular Weight | 384.47 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H24N4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HS-1371HS-1371 is a potent and ATP-competitive RIP3 inhibitor with an IC50 of 20.8 nM[1]. |
| Name | HS-1371 |
|---|
| Description | HS-1371 is a potent and ATP-competitive RIP3 inhibitor with an IC50 of 20.8 nM[1]. |
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| Related Catalog | |
| Target |
IC50: 20.8 nM (RIP3)[1] |
| In Vitro | HS-1371 directly binds to RIP3 in an ATP-competitive and time-independent manner. HS-1371 has an inhibitory effect on RIP3 kinase activity in various cell lines[1]. HS-1371 can block RIP3 S227 phosphorylation[1]. HS-1371 rescues cells from RIP3-dependent necroptotic cell death but not apoptotic cell death[1]. |
| References |
| Molecular Formula | C24H24N4O |
|---|---|
| Molecular Weight | 384.47 |
| Storage condition | 2-8℃ |