Fmoc-PEG3-CH2CO2-NHS

Modify Date: 2024-01-11 22:56:43

Fmoc-PEG3-CH2CO2-NHS Structure
Fmoc-PEG3-CH2CO2-NHS structure
Common Name Fmoc-PEG3-CH2CO2-NHS
CAS Number 2128735-25-9 Molecular Weight 526.54
Density N/A Boiling Point N/A
Molecular Formula C27H30N2O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Fmoc-PEG3-CH2CO2-NHS


Fmoc-N-PEG3-CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Fmoc-N-PEG3-CH2-NHS ester
Synonym More Synonyms

 Fmoc-PEG3-CH2CO2-NHS Biological Activity

Description Fmoc-N-PEG3-CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C27H30N2O9
Molecular Weight 526.54

 Synonyms

MFCD31536755